Background: There is a vast amount of published articles, centered on tethered cord syndrome, which is related to a constellation of diverse pathological entities, included under the term occult spinal dysraphism.Objective: To present the 100 most-cited articles dedicated to the entity of tethered cord syndrome and to present a comprehensive review
Imidacloprid is a neonicotinoid neurotoxin that remains widely used worldwide and persists in the environment, resulting in chronic exposure to non-target insects.To accurately map dose-dependent effects of such exposure across taxa, toxicological assays need to assess relevant modes of exposure across indicator species.However, due to the difficul
The search for safe and efficient chronic pain treatments is dampened by the lack of reliable models that faithfully reproduce current pharmacological treatments for chronic spontaneous pain in humans.Preclinical models often assess the antinociceptive efficacy Mantle Clock of non-contingent pharmacological treatments evaluated in the short-term.He
Hyperglycemia induces chronic inflammation and oxidative stress in cardiomyocyte, which are the main pathological changes of diabetic cardiomyopathy (DCM).Treatment aimed at these processes may be beneficial in DCM.Phloretin (PHL), a promising natural product, has many pharmacological activities, such as anti-inflammatory, anticancer, and anti-oxid